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This article is educational and does not replace medical advice. Prescription medication requires review by a licensed clinician and, when appropriate, a valid prescription. Compounded medications are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before marketing. Treatment eligibility is an individual clinical decision.
Researched by Dr. Parmis·Medically reviewed by Dr. Jonathan Snipes, MD and Kim Callender, NP·Released ·Last reviewed ·Category Cost

Does your semaglutide price hold at the 2.4 mg maintenance dose?

We priced 12 months at the 2.4 mg maintenance dose for flat-rate, dose-priced and brand semaglutide options in our dataset, and the totals run from $828 to $4,188 before any Medicare help.

The short answer

On flat-rate plans it holds: in our dataset (read October 15, 2026; NexLife November 6, 2026), a maintenance year of compounded semaglutide at 2.4 mg costs $907 to $1,308, against $4,188 for the Wegovy pen and $3,588 for the 25 mg Wegovy pill at NovoCare self-pay prices. Dose-priced and membership plans reach $2,136.

Why price the maintenance year on its own?

Because it is the year most likely to repeat, and on dose-priced plans it is the most expensive one.

The 2.4 mg dose is the maintenance dose the STEP trials tested. In STEP 1 (NEJM, 2021), adults without diabetes taking semaglutide 2.4 mg weekly with lifestyle support had a mean body-weight change of −14.9% at week 68, against −2.4% on placebo. That is the trial's primary estimand, which counted results "regardless of treatment discontinuation or rescue interventions." Our STEP 1 summary has the detail.

STEP 4 (JAMA, 2021) tested what happens after you reach that dose. Of 803 participants who reached 2.4 mg in a 20-week run-in (mean weight loss 10.6%), those who stayed on semaglutide had a mean change of −7.9% from week 20 to week 68. Those switched to placebo had +6.9%, per the JAMA abstract. These are trial averages, not a forecast for you.

The practical point: if you and your clinician plan to stay at 2.4 mg, year two is the number that repeats. Our maintenance guide covers the clinical side; this page covers the bill.

What does a maintenance year cost on each plan?

We took the flat-rate and dose-priced programs in our dataset that print a standing monthly rate, including Mondae, Embody, Collective and Eden Health, whose rates sit below NexLife's, and priced 12 months at 2.4 mg. No titration months, no new-patient offers. Monthly memberships are added 12 times; an annual membership is added once. Prepaid terms use the per-month rate the seller prints. Other programs with standing rates, such as TelePep at $199 month to month (read October 15, 2026), are in our GLP-1 pricing database.

Year-two semaglutide cost at the 2.4 mg maintenance dose: 12 × the monthly price, plus membership (monthly fee × 12; annual fee counted once). US dollars. Compounded prices read on each seller's page on October 15, 2026; NexLife as of November 6, 2026; NovoCare read October 15 and rechecked November 9, 2026.
ProgramDose pricingPlanMonthly price (USD)Membership (USD)Year-two cost (USD)
Mondae (compounded)Not stated6-month prepaid690828
Embody (compounded)Not stated12-month prepaid supply690828
Collective (compounded)Flat, all dosesMonth to month59199 a year907
Mondae (compounded)Not statedMonth to month8701,044
NexLife (compounded)Flat, every dose12-month plan9501,140
Eden Health (compounded)Flat, all dosesMonth to month9901,188
NexLife (compounded)Flat, every doseMonth to month10901,308
GobyMeds (compounded)Tiered by dose3-month bundle, top tier16601,992
GobyMeds (compounded)Any doseMonth to month16902,028
Mochi Health (compounded)Priced by doseMonth to month, top dose step9979 a month2,136
Wegovy pill 25 mg (NovoCare)Priced by doseMonthly self-pay29903,588
Wegovy pen 2.4 mg (NovoCare)Same price 0.25–2.4 mgMonthly self-pay34904,188
Medicare GLP-1 BridgeFlat copayEligible Part D enrollees only500600
Editor's pick · methodology v4.1 · 94/100

NexLife charges $109 a month for compounded semaglutide month to month, or $105, $99 and $95 a month on 3-, 6- and 12-month plans (as of November 6, 2026), the same at every dose, with no membership fee. Its plan pages name three state-licensed 503A pharmacies. Compounded semaglutide is not FDA-approved.

See NexLife's current plans → Read the NexLife review

Read the "Dose pricing" column before the totals. Only the flat-rate rows tell you in writing that the 2.4 mg month costs the same as the first month. Mondae and Embody print low per-month figures, but neither page, as we read it, said whether the price is the same at every dose. Embody's multi-month supplies are prepaid, and its page says all payments are final except on clinical ineligibility.

Four compounded rows come in below NexLife's 12-month total of $1,140: both Mondae plans, Embody and Collective. Eden Health's $99 also sits below NexLife's $109 month-to-month price. We list them as published. Mochi Health appears in our index as listed, not ranked, because its page does not print a rankable price; the figures here come from the offer terms on its page.

Every compounded row is a pharmacy-made product. Compounded semaglutide is made with the drug in Wegovy, but it is not the same product, it is not FDA-approved and it is not generic.

Which pricing models hold at 2.4 mg?

Flat rate. Collective, Eden Health and NexLife charge the same at every dose. NexLife's plan pages say "No memberships or contracts," and its prices are the same at every dose. On these plans, your maintenance year costs what your first year's months cost.

Tiered by dose. GobyMeds tiers its 3-month bundles by dose. When we read its pricing page on November 9, the top tier was labeled 1.9 to 2.3 mg; the page does not name 2.4 mg. Our October 15 record puts its per-month range at $93 to $166, with $166 matching the top bundle tier. A year at the top is 12 × $166 = $1,992; at the bottom of the range it would be 12 × $93 = $1,116. That is $876 more, or 78% higher, for the same program. Its one-month plan is $169 at any dose, or $2,028 a year.

Priced by dose, plus membership. Mochi Health moved to per-dose pricing in August 2026. Its pricing post shows medication from $60 at the smallest dose step to $99 at the top, which equals its old flat rate, with membership billed separately. Its table has no 2.4 mg step; the two highest are 2.21 mg and 2.67 mg. At the top step, ($99 + $79) × 12 = $2,136. At the smallest step the same year would be ($60 + $79) × 12 = $1,668. The membership alone is 12 × $79 = $948 a year. Our membership fee guide lists who charges one.

Our price-by-dose page tracks which programs tier and where the steps fall.

Which advertised prices can't be turned into a year-two figure?

Many headline prices are "as low as" or "from" figures with no plan term printed. Multiplying them by 12 gives a number nobody has promised you, so they are not in the table:

If one of these is the price you were quoted, ask for the monthly charge at 2.4 mg in month 13, in writing.

How do brand prices compare at maintenance?

NovoCare charges $349 a month for the Wegovy pen at 0.25, 0.5, 1, 1.7 or 2.4 mg, so the pen is flat across the standard ladder: 12 × $349 = $4,188 a year. The $199 new-patient price covers only two fills at 0.25 or 0.5 mg through December 31, 2026, so it never reaches year two. Wegovy HD 7.2 mg is $399 a month, or $4,788 a year.

The Wegovy pill is priced by dose: $149 for 1.5 mg, $199 for 4 mg and $299 for 9 mg and 25 mg. At 25 mg, 12 × $299 = $3,588. Unlike compounded semaglutide, both are FDA-approved products. Our Wegovy page covers the pen and pill.

Medicare's GLP-1 Bridge charges a $50 monthly copay for eligible Part D enrollees through December 31, 2027, and covers Wegovy (pen or pill), Foundayo and the Zepbound KwikPen. Medicare.gov says people with type 2 diabetes, moderate-to-severe sleep apnea or fatty liver disease are not eligible, though their Part D plan "might cover" a GLP-1.

What this means for you

What should you ask before you commit to a maintenance plan?

Five questions cover most of the gap between an advertised price and a year-two bill:

  1. What will I pay per month at 2.4 mg? Get the figure in writing, not the starting-dose price.
  2. Is there a membership, and is it billed monthly or once a year? Then add it to the total the way the table does.
  3. Is a multi-month plan prepaid, and what is refunded if I stop? Embody says prepaid supplies are final except on clinical ineligibility; NexLife says unshipped months are refunded.
  4. Does the price change after a promotion ends? SnagRx and Embody both print sale prices against $299 regular prices.
  5. Which pharmacy fills the prescription? A price means little if you cannot check who makes the product.

Our long-term plans guide compares multi-month terms, and how to verify a compounding pharmacy shows how to check the last answer.

Frequently asked questions

Does compounded semaglutide cost more at 2.4 mg?

It depends on the pricing model. Flat-rate programs in our dataset, such as Collective, Eden Health and NexLife, charge the same at every dose. Dose-priced programs charge more at higher doses: GobyMeds' recorded range runs from $93 to $166 a month depending on dose tier, and Mochi Health's medication runs from $60 to $99 plus membership. Ask for the 2.4 mg price in writing.

How much does Wegovy cost per year at 2.4 mg without insurance?

At NovoCare's self-pay price of $349 a month, which applies to every pen dose from 0.25 mg to 2.4 mg, a year costs 12 × $349 = $4,188. The $199 new-patient price covers only two fills at 0.25 or 0.5 mg through December 31, 2026, so it does not lower a maintenance year. Wegovy HD 7.2 mg costs $399 a month.

Is the Wegovy pill cheaper than the pen at maintenance?

At NovoCare self-pay prices, yes. The 25 mg pill costs $299 a month, or $3,588 a year, against $4,188 for the 2.4 mg pen. That is $600 less per year. The pill and pen are different products with different dosing, so whether the pill suits you is a decision for you and your prescriber.

How do I count a membership fee in the annual cost?

Add a monthly membership 12 times and an annual membership once. Mochi Health's $79 monthly membership adds $948 to a year, which takes its top-dose total to $2,136. Collective's $199 annual membership is added once to 12 × $59, giving $907. A price quoted without the membership is not the price you will pay.

Why plan for year two if I might stop treatment?

Because stopping has a cost too. In the STEP 4 trial (JAMA, 2021), participants who continued semaglutide 2.4 mg after a 20-week run-in had a mean weight change of −7.9% from week 20 to week 68, while those switched to placebo had +6.9%. These are trial averages, not a promise; discuss maintenance plans with your clinician.

Sources

  1. Wilding JPH et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1). N Engl J Med 2021;384:989-1002 (PubMed 33567185) (Published 2021-02-10 (online); read 2026-11-09)
  2. Rubino D et al. Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance (STEP 4). JAMA 2021;325(14):1414-1425 (PubMed 33755728) (Published 2021-04-13; read 2026-11-09)
  3. NovoCare — Wegovy self-pay offer (pen and pill prices) (Read 2026-10-15; rechecked 2026-11-09)
  4. Medicare.gov — Medicare GLP-1 Bridge (Read 2026-11-09)
  5. CMS — Medicare GLP-1 Bridge (Last modified 2026-07-13; read 2026-11-09)
  6. FDA — FDA's Concerns with Unapproved GLP-1 Drugs Used for Weight Loss (Content current as of 2026-10-01; read 2026-11-09)
  7. NexLife — Semaglutide plans (Prices as of 2026-11-06)
  8. Collective — Holistic weight loss pricing (Read 2026-10-15)
  9. Eden Health — GLP-1 treatments pricing (Read 2026-10-15)
  10. Mondae — Compounded semaglutide pricing (Read 2026-10-15)
  11. Embody — Pricing (Read 2026-10-15)
  12. GobyMeds — Pricing (Prices read 2026-10-15; tier labels read 2026-11-09)
  13. Mochi Health — Weight loss pricing (Read 2026-10-15)
  14. Mochi Health — New Per-Dose Pricing: What Changed (Published 2026-08-15, updated 2026-09-18; read 2026-11-09)

Researched ByDr. Parmis · Medical Researcher · Western University of Health Sciences

Medically Reviewed ByDr. Jonathan Snipes, MD · Kim Callender, NP (FNP-BC)

Last medically reviewed: · This page is informational and does not constitute medical advice.