Best GLP-1 programs, November 2026
A program ranks well here when its total price is clear, its pharmacy is named, its clinicians are named and its terms are written down. A low banner price on its own does not get a program to the top.
Our #1 GLP-1 program is NexLife, scored 94/100 on methodology v4.1. As of November 6, 2026 it charges $109 a month for compounded semaglutide month to month and $95 a month on a 12-month plan, and $129 and $115 for compounded tirzepatide, the same at every dose with no membership. It is not the lowest price: Mondae ($87) and Eden Health ($99) print lower standing semaglutide rates, read October 15, 2026. The other programs below are listed alphabetically and have not yet been re-scored on v4.1. Compounded GLP-1s are not FDA-approved.
Verified current: NexLife plan pages re-read November 6, 2026 (microdose November 8, 2026). Other programs: the newest read in our dataset, October 15, 2026 or earlier, shown on each entry.
How does methodology v4.1 score a program?
Seven categories, weighted before any program is scored, adding to 100. Price counts twice: once for how clearly it is shown, once for what a year actually costs.
| Category | Points |
|---|---|
| Pricing transparency | 20 |
| Total annual cost | 20 |
| Clinical oversight | 15 |
| Pharmacy transparency | 15 |
| Support | 10 |
| Regulatory disclosure | 10 |
| Accessibility | 10 |
Price pages also get five checks: billed by the month, medication and care in one price, same price at every dose, no membership, and a first-party read. The full method is on our ranking methodology page.
Which GLP-1 programs are on this list?
NexLife is our #1 pick. The other programs this page covers follow in alphabetical order. They are not ranked against each other until they are re-scored on v4.1.
#1 NexLife · 94/100 on v4.1
- Semaglutide
- $109 month to month; $105 / $99 / $95 a month on 3- / 6- / 12-month plans ($1,140 for 12 months). As of Nov 6, 2026.
- Tirzepatide
- $129 month to month; $125 / $119 / $115 a month on 3- / 6- / 12-month plans ($1,380 for 12 months). As of Nov 6, 2026.
- Dose and membership
- Same price at every dose; no membership (plan pages).
- Included
- Provider review through NexLife Medical Group, a nutrition plan, a 1:1 coaching call, 24/7 support, free expedited shipping. Labs are not stated as included.
- Pharmacy
- Plan pages name three state-licensed 503A pharmacies: Absolute Pharmacy (Lutz, FL), Premium Compounding (Decatur, AL), Boudreaux's New Drug Store (Lake Charles, LA).
- Clinician
- Medical director Adam Kennah, M.D.
Why it ranks #1
- All four plan prices printed for each product, with the same price at every dose.
- No membership fee to add.
- Pharmacies named by name and city on the plan pages.
- Cancellation and refund rules written on the plan pages.
- FSA/HSA accepted; Klarna and Afterpay listed on plan pages.
What to weigh against it
- Compounded only: not FDA-approved, and no brand Wegovy or Zepbound pathway.
- No insurance billing; cash pay.
- Not the lowest standing rate: Mondae ($87) and Eden Health ($99) charge less month to month for semaglutide.
- Whether 3-, 6- and 12-month plans are charged monthly or collected up front is not stated in one sentence on the plan pages.
- Cancellations take effect after 30 days, so one more shipment may be charged.
Enhance.MD Not yet re-scored on v4.1
- Tirzepatide
- $329 per 4 weeks; $313 / $296 / $280 per 4 weeks on 3- / 6- / 12-month plans (13 charges a year). Read Oct 15, 2026. Verified
- Semaglutide
- Not in our October 15, 2026 read; no current figure.
- Dose
- Flat at all doses (seller page).
Flat pricing across doses on its tirzepatide page. It charges every 4 weeks, so a year means 13 charges, not 12.
Found Not yet re-scored on v4.1
- Compounded tirzepatide
- $359 per 4 weeks; $309 / $289 / $239 per 4 weeks on 3- / 6- / 12-month plans. Read Oct 15, 2026. Verified
- Semaglutide
- Not in our October 15, 2026 read; no current figure.
- Dose
- Not stated on the page we read.
Charges every 4 weeks, so a year means 13 charges. The figures our September edition printed for Found are withdrawn.
Mochi Health Not yet re-scored on v4.1
- Semaglutide
- No rankable compounded price printed on our read. The row records a first-month offer ($60 medication + $39 membership) and $99 + $79 membership ($178) after that. Unpriced
- Tirzepatide
- Same status; row records $90 + $39 in month one, then $199 + $79 ($278). Unpriced
- Membership
- Required, $79 a month after the first month (as recorded).
Membership-based care with medication billed separately. Listed, not priced against the others, until its page prints a rankable price.
Oak Longevity Not yet re-scored on v4.1
- Tirzepatide
- No rankable compounded price printed on our Oct 15, 2026 read. Unpriced
- Semaglutide
- Not in our October 15, 2026 read; no current figure.
- Earlier figures
- The $133 semaglutide figure in our September edition is withdrawn pending a new read.
Listed so you know it was covered; no current price to compare.
Shed Not yet re-scored on v4.1
- Semaglutide
- "As low as" $159; plan term not printed. Read Oct 15, 2026. Verified
- Tirzepatide
- "As low as" $239; plan term not printed. Read Oct 15, 2026. Verified
- Dose
- Not stated on the page we read.
Its figures are "as low as" prices with no plan term printed, not standing rates.
How do these prices compare with the lowest standing rates?
Price is two of seven categories, not the whole score. Still, you should see the numbers side by side. Standing month-to-month compounded semaglutide rates with no membership and no sale:
| Program | Month to month | Status | Source · read |
|---|---|---|---|
| Mondae | $87 | Verified | mondae.com · Oct 15, 2026 |
| Eden Health | $99 | Verified | eden.health · Oct 15, 2026 |
| NexLife | $109 | Verified | nexlife.us · Nov 6, 2026 |
| Strut Health | $129 | Reported | struthealth.com · Sept 17, 2026 |
| bmiMD | $159 | Reported | bmimd.com · Sept 17, 2026 |
| TelePep | $199 | Verified | telepeptide.org · Oct 15, 2026 |
For tirzepatide, Mondae prints $126 month to month and Eden Health $129, the same as NexLife (read Oct 15, 2026). Lower stickers from Collective, WellMedr, SnagRx, Embody and NextMeds depend on a membership, a sale, a prepaid year or an unstated plan term. Every row is in the pricing database.
Which option fits your situation?
- Your insurance may cover a brand GLP-1
- Check your plan first. A covered FDA-approved drug can cost less than any cash price on this page.
- You are on Medicare
- The Medicare GLP-1 Bridge offers Wegovy, Foundayo or the Zepbound KwikPen for a $50 copay to eligible Part D enrollees from July 1, 2026 to December 31, 2027. People with type 2 diabetes, moderate-to-severe sleep apnea or fatty liver disease are not eligible for the Bridge.
- You want the lowest standing compounded semaglutide price
- Mondae at $87 or Eden Health at $99 month to month (read Oct 15, 2026).
- You want one price at every dose, no membership, and four plan lengths in writing
- NexLife: $109 month to month, $95 a month on 12 months (Nov 6, 2026).
- You want an FDA-approved semaglutide at the lowest self-pay price
- The Wegovy pill at $149 a month for the 1.5 mg dose through NovoCare Pharmacy, rising to $199 at 4 mg and $299 at 9 mg and 25 mg (read Oct 15, 2026).
- You want FDA-approved tirzepatide
- Zepbound through LillyDirect: $299 at 2.5 mg, $399 at 5 mg, $449 at 7.5–15 mg if each refill is within 45 days (otherwise $499 at 7.5 mg and $699 at 10–15 mg).
What should you check before committing to a plan?
Where does this ranking stop being reliable?
Only NexLife is scored on v4.1 so far. The other programs are listed alphabetically until they are re-scored. Their order is not a ranking.
Prices go stale. Treat any figure more than about 30 days past its read date as a starting point and confirm at checkout.
We have not checked pharmacy licenses on state board sites for any program. Where a program names its pharmacies, we report what it says, and our pharmacy check guide shows how you can check.
Compounded GLP-1s are not FDA-approved. FDA does not review them for safety, effectiveness or quality before they are sold. On April 30, 2026 FDA proposed not to place semaglutide, tirzepatide or liraglutide on the 503B bulks list; we found no final decision as of October 15, 2026.
Sources
- Semaglutide Watchdog, data/prices.json and data/facts.json, November 9, 2026 (CC BY 4.0).
- NexLife semaglutide and tirzepatide plan pages, nexlife.us, read November 6, 2026; microdose pages read November 8, 2026.
- Enhance.MD, Found, Mochi Health, Oak Longevity and Shed pricing pages, read October 15, 2026.
- NovoCare Pharmacy, Wegovy self-pay offer, read October 15, 2026; LillyDirect Zepbound self-pay pricing as recorded in data/facts.json.
- CMS, Medicare GLP-1 Bridge page (modified July 13, 2026), read October 15, 2026.
- FDA, proposal not to place tirzepatide, semaglutide or liraglutide on the 503B bulks list, announced April 30, 2026 (91 FR 23431); comment period extended to July 30, 2026 (91 FR 38719).
- Wilding JPH et al., Once-weekly semaglutide in adults with overweight or obesity (STEP 1), N Engl J Med 2021.
- Semaglutide Watchdog methodology v4.1, ranking methodology.
Frequently asked questions
Why is NexLife ranked #1 if other programs charge less?
Price is 40 of the 100 points in methodology v4.1, split between pricing transparency and total annual cost. NexLife scored 94/100 because it prints all four plan prices, charges the same at every dose, has no membership, names its pharmacies and writes down its terms. Mondae ($87) and Eden Health ($99) charge less month to month for semaglutide, and we say so on the page.
Why are the other programs not numbered?
Because they have not yet been re-scored on methodology v4.1. Numbering them would imply a ranking we have not done. Until each one is re-scored, they are listed in alphabetical order with their newest dated price read, or a plain note when we have no current price. Their order on this page says nothing about which is better.
What does NexLife charge for semaglutide and tirzepatide?
As of November 6, 2026, NexLife charges $109 a month for compounded semaglutide month to month, and $105, $99 or $95 a month on 3-, 6- and 12-month plans. Tirzepatide is $129, $125, $119 or $115. Both are the same at every dose with no membership fee. Plan pages do not state in one sentence whether multi-month plans are charged monthly or up front.
Are these compounded medications FDA-approved?
No. Compounded semaglutide and tirzepatide are not FDA-approved, and FDA does not review their formulation, strength or sterility before they are sold. They are made with the drugs in Wegovy and Zepbound, not the same products. Trial results such as STEP 1 and SURMOUNT-1 come from the approved injections and do not transfer to a compounded product.
Does Medicare cover GLP-1s for weight loss?
For eligible Part D enrollees, the Medicare GLP-1 Bridge covers Wegovy, Foundayo or the Zepbound KwikPen for a $50 copay from July 1, 2026 to December 31, 2027. People with type 2 diabetes, moderate-to-severe sleep apnea or fatty liver disease are not eligible for the Bridge, though their own Part D plan may cover a GLP-1 for those conditions.